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Researcher in Laboratory © HIPS

Franziska Fries

About

Franziska Fries studied pharmacy at Saarland University in Saarbrücken, where she was awarded the Deutschlandstipendium for her outstanding academic achievements. In 2020, she completed her master's thesis in the Microbial Natural Products department of Prof. Dr. Müller, working on the establishment of a Staphylococcus aureus infection model in zebrafish larvae to investigate new potential active compounds in vivo at an early stage.

After successful licensure as a pharmacist in 2021, Franziska returned to HIPS and continues her work as a PhD student. Franziska’s research focuses on target identification and mode-of-action studies of novel antimicrobial natural products as well as the investigation of their ADME-Tox properties using zebrafish larvae.


2024

The Peptide Antibiotic Corramycin Adopts a β-Hairpin-like Structure and Is Inactivated by the Kinase ComG

Adam S, Fries F, Tesmar A, Rasheed S, Deckarm S, Sousa C, Reberšek R, Risch T, Mancini S, Herrmann J, …, Kalinina O, Müller R (2024)

J. Am. Chem. Soc.DOI: 10.1021/jacs.3c13208

2023

Impact of Drug Administration Routes on the In Vivo Efficacy of the Natural Product Sorangicin a Using a Staphylococcus aureus Infection Model in Zebrafish Embryos

Fries F, Kany A, Rasheed S, Hirsch A, Müller R, Herrmann J (2023)

International journal of molecular sciences 24 (16)DOI: 10.3390/ijms241612791

2021

Zebrafish: An Attractive Model to Study Staphylococcus aureus Infection and Its Use as a Drug Discovery Tool

Rasheed S, Fries F, Müller R, Herrmann J (2021)

Pharmaceuticals 14 (6)DOI: 10.3390/ph14060594