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Christoph Porten

About

After completing his training as a chemical laboratory technician, Christoph Porten studied Applied Pharmacy at Kaiserslautern University of Applied Sciences, with a focus on regulatory affairs and analytics. He subsequently deepened his expertise in analytical chemistry and bioanalysis by completing a Master’s degree in Bioanalysis at Coburg University of Applied Sciences.

From 2021 to 2025, he conducted his doctoral research in the research group of Rolf Müller. His dissertation focused on the development and validation of analytical methods, particularly RP-UPLC-MS. In addition, the work included the optimization of extraction and purification processes as well as the application of proteomics and metabolomics analyses with statistical data evaluation and visualization. Furthermore, he served as a laboratory administrator, with responsibility for analytical instrumentation and data analysis software, including troubleshooting and staff training.

Since then, he has been working as a postdoctoral researcher with a focus on analytical method development and metabolomics.


2024

In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens

Kany A, Fries F, Seyfert C, Porten C, Deckarm S, Chacón Ortiz M, Dubarry N, Vaddi S, Große M, Bernecker S, …, Herrmann J, Müller R (2024)

ACS Infect. Dis. 10 (12): 4337-4346DOI: 10.1021/acsinfecdis.4c00687

2023

Darobactine: eine neue Antibiotikaklasse in Entwicklung

Seyfert C, Porten C, Müller R (2023)

Biospektrum 29 (5): 539-541DOI: 10.1007/s12268-023-1988-6

New Genetically Engineered Derivatives of Antibacterial Darobactins Underpin Their Potential for Antibiotic Development

Seyfert C, Müller A, Walsh D, Birkelbach J, Kany A, Porten C, Yuan B, Krug D, Herrmann J, Marlovits T, Hirsch A, Müller R (2023)

J. Med. Chem.DOI: 10.1021/acs.jmedchem.3c01660

New Genetically Engineered Derivatives of Antibacterial Darobac-tins Underpin their Potential for Antibiotic Development

Seyfert C, Müller A, Walsh D, Birkelbach J, Kany A, Porten C, Yuan B, Krug D, Herrmann J, Marlovits T, Hirsch A, Müller R (2023)

BookDOI: 10.26434/chemrxiv-2023-24tmj

2022

Darobactins Exhibiting Superior Antibiotic Activity by Cryo-EM Structure Guided Biosynthetic Engineering

Seyfert C, Porten C, Yuan B, Deckarm S, Panter F, Bader C, Coetzee J, Deschner F, Tehrani K, Higgins P, …, Herrmann J, Müller R (2022)

Angewandte Chemie (International ed. in English)DOI: 10.1002/anie.202214094