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Chorismatases - the family is growing
Publication
Grüninger M,
Buchholz P,
Mordhorst S,
Strack P,
Müller M,
Hubrich F,
Pleiss J,
Andexer J
(2019)
Org. Biomol. Chem., 17, 8, 2092-2098, 10.1039/c8ob03038c, 30706936
Org. Biomol. Chem., 17, 8, 2092-2098, 10.1039/c8ob03038c, 30706936
Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro4.4non-8-ene
Publication
Fu C,
Xie F,
Hoffmann J,
Wang Q,
Bauer A,
Brönstrup M,
Mahmud T,
Müller R
(2019)
ChemBioChem, 20, 6, 764-769, 10.1002/cbic.201800791, 30556942
ChemBioChem, 20, 6, 764-769, 10.1002/cbic.201800791, 30556942
Solving the puzzle of the one-carbon loss in ripostatin biosynthesis
Publication
Fu C,
Auerbach D,
Li Y,
Scheid U,
Luxenburger E,
Garcia R,
Irschik H,
Müller R
(2017)
Angew. Chem. Int. Ed. Engl., 56, 8, 2192-2197, 10.1002/anie.201609950
Angew. Chem. Int. Ed. Engl., 56, 8, 2192-2197, 10.1002/anie.201609950
Isolation, structure elucidation, and (bio)synthesis of Haprolid, a cell-type-specific myxobacterial cytotoxin
Publication
Steinmetz H,
Li J,
Fu C,
Zaburannyi N,
Kunze B,
Harmrolfs K,
Schmitt V,
Herrmann J,
Reichenbach H,
Hofle G,
Kalesse M,
Müller R
(2016)
Angew. Chem. Int. Ed. Engl., 55, 34, 10113-7, 10.1002/anie.201603288, 27404448
Angew. Chem. Int. Ed. Engl., 55, 34, 10113-7, 10.1002/anie.201603288, 27404448
Biosynthetic studies of telomycin reveal new lipopeptides with enhanced activity
Publication
Fu C,
Keller L,
Bauer A,
Brönstrup M,
Froidbise A,
Hammann P,
Herrmann J,
Mondesert G,
Kurz M,
Schiell M,
Schummer D,
Toti L,
Wink J,
Müller R
(2015)
J. Am. Chem. Soc., 137, 24, 7692-7705, 10.1021/jacs.5b01794, 26043159
J. Am. Chem. Soc., 137, 24, 7692-7705, 10.1021/jacs.5b01794, 26043159
Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold
Publication
Hubrich F,
Juneja P,
Müller M,
Diederichs K,
Welte W,
Andexer J
(2015)
J. Am. Chem. Soc., 137, 34, 11032-7, 10.1021/jacs.5b05559, 26247872
J. Am. Chem. Soc., 137, 34, 11032-7, 10.1021/jacs.5b05559, 26247872
Mechanistic implications for the chorismatase FkbO based on the crystal structure
Publication
Juneja P,
Hubrich F,
Diederichs K,
Welte W,
Andexer J
(2014)
J. Mol. Biol., 426, 1, 105-15, 10.1016/j.jmb.2013.09.006, 24036425
J. Mol. Biol., 426, 1, 105-15, 10.1016/j.jmb.2013.09.006, 24036425
Cinnamic acid derivatives as inhibitors for chorismatases and isochorismatases
Publication
Hubrich F,
Mordhorst S,
Andexer J
(2013)
Bioorg. Med. Chem. Lett., 23, 5, 1477-81, 10.1016/j.bmcl.2012.12.059, 23380376
Bioorg. Med. Chem. Lett., 23, 5, 1477-81, 10.1016/j.bmcl.2012.12.059, 23380376
Engineering the respiratory complex I to energy-converting NADPH:ubiquinone oxidoreductase
Publication
Morina K,
Schulte M,
Hubrich F,
Dörner K,
Steimle S,
Stolpe S,
Friedrich T
(2011)
J. Biol. Chem., 286, 40, 34627-34, 10.1074/jbc.M111.274571, 21832062
J. Biol. Chem., 286, 40, 34627-34, 10.1074/jbc.M111.274571, 21832062
Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model
Publication
Kiefer A,
Schütz C,
Englisch C,
Kolling D,
Speicher S,
Kany A,
Shafiei R,
Wadood N,
Aljohmani A,
Wirschem N,
Jumde R,
Klein A,
Sikandar A,
Park Y,
Krasteva-Christ G,
Yildiz D,
Abdelsamie A,
Rox K,
Köhnke J,
Müller R,
Bischoff M,
Haupenthal J,
Hirsch A
(2025)
Adv. Sci., 10.1002/advs.202411807, 39973061
Adv. Sci., 10.1002/advs.202411807, 39973061