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Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening
Publication
Di Zhu,
Johannsen S,
Masini T,
Simonin C,
Haupenthal J,
Illarionov B,
Andreas A,
Awale M,
Gierse R,
van der Laan T,
van der Vlag R,
Nasti R,
Poizat M,
Buhler E,
Reiling N,
Müller R,
Fischer M,
Reymond J,
Hirsch A
(2022)
Chem. Sci., 13, 36, 10686-10698, 10.1039/D2SC02371G, 36320685
Chem. Sci., 13, 36, 10686-10698, 10.1039/D2SC02371G, 36320685
Large-Scale Interlaboratory DI-FT-ICR MS Comparability Study Employing Various Systems
Publication
Forcisi S,
Moritz F,
Thompson C,
Kanawati B,
Uhl J,
Afonso C,
Bader C,
Barsch A,
Boughton B,
Chu R,
Ferey J,
Fernandez-Lima F,
Guéguen C,
Heintz D,
Gomez-Hernandez M,
Jang K,
Kessler N,
Mangal V,
Müller R,
Nakabayashi R,
Nicol E,
Nicolardi S,
Palmblad M,
Paša-Tolic L,
Porter J,
Schmitz-Afonso I,
Seo J,
Sommella E,
van der Burgt Y,
Villette C,
Witt M,
Wittrig A,
Wolff J,
Easterling M,
Laukien F,
Schmitt-Kopplin P
(2022)
Journal of the American Society for Mass Spectrometry, 10.1021/jasms.2c00082, 36371691
Journal of the American Society for Mass Spectrometry, 10.1021/jasms.2c00082, 36371691
Pineapple Lectin AcmJRL binds SARS-CoV-2 Spike Protein in a carbohydrate-dependent fashion
Publication
Meiers J,
Dastbaz J,
Adam S,
Rasheed S,
Kirsch S,
Meiser P,
Gross P,
Müller R,
Titz A
(2022)
Chembiochem : a European journal of chemical biology, 10.1002/cbic.202200463, 36420784
Chembiochem : a European journal of chemical biology, 10.1002/cbic.202200463, 36420784
Sesbanimide R, a Novel Cytotoxic Polyketide Produced by Magnetotactic Bacteria
Publication
Awal R,
Haack P,
Bader C,
Riese C,
Schüler D,
Müller R
(2021)
mBio, 12, 3, 10.1128/mBio.00591-21, 34006654
mBio, 12, 3, 10.1128/mBio.00591-21, 34006654
Improved broad-spectrum antibiotics against Gram-negative pathogens via darobactin biosynthetic pathway engineering
Publication
Groß S,
Panter F,
Pogorevc D,
Seyfert C,
Deckarm S,
Bader C,
Herrmann J,
Müller R
(2021)
Chem. Sci., 12, 35, 11882-11893, 10.1039/d1sc02725e, 34659729
Chem. Sci., 12, 35, 11882-11893, 10.1039/d1sc02725e, 34659729
The Sandarazols are Cryptic and Structurally Unique Plasmid-Encoded Toxins from a Rare Myxobacterium*
Publication
Panter F,
Bader C,
Müller R
(2021)
Angewandte Chemie (International ed. in English), 60, 15, 8081-8088, 10.1002/anie.202014671, 33534143
Angewandte Chemie (International ed. in English), 60, 15, 8081-8088, 10.1002/anie.202014671, 33534143
Synergizing the potential of bacterial genomics and metabolomics to find novel antibiotics
Publication
Panter F,
Bader C,
Müller R
(2021)
Chem. Sci., 12, 17, 5994-6010, 10.1039/d0sc06919a, 33995996
Chem. Sci., 12, 17, 5994-6010, 10.1039/d0sc06919a, 33995996
Supercritical Fluid Extraction Enhances Discovery of Secondary Metabolites from Myxobacteria
Publication
Bader C,
Neuber M,
Panter F,
Krug D,
Müller R
(2020)
Analytical chemistry, 92, 23, 15403-15411, 10.1021/acs.analchem.0c02995, 33171050
Analytical chemistry, 92, 23, 15403-15411, 10.1021/acs.analchem.0c02995, 33171050
Protein‐Templated Hit Identification via an Ugi Four‐Component Reaction
Publication
Mancini F,
Unver M,
Elgaher W,
Jumde V,
Alhayek A,
Lukat P,
Herrmann J,
Witte M,
Köck M,
Blankenfeldt W,
Müller R,
Hirsch A
(2020)
Chem. Eur. J., 10.1002/chem.202002250
Chem. Eur. J., 10.1002/chem.202002250
Synthesis and Biological Evaluation of Novel 2-Substituted Analogues of (–)-Pentenomycin I
Publication
Zisopoulou S,
Bousis S,
Haupenthal J,
Herrmann J,
Müller R,
Hirsch A,
Komiotis D,
Gallos J,
Stathakis C
(2020)
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772
Synlett, 31, 05, 475-481, 10.1055/s-0039-1690772