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The biosynthetic potential of myxobacteria and their impact on drug discovery
Publication
Wenzel S,
Müller R
(2009)
Curr. Opin. Drug Discov. Devel., 12, 2, 220-230
Curr. Opin. Drug Discov. Devel., 12, 2, 220-230
The impact of genomics on the exploitation of the myxobacterial secondary metabolome
Publication
Wenzel S,
Müller R
(2009)
Nat. Prod. Rep., 26, 11, 1385-1407, 10.1039/b817073h, 19844638
Nat. Prod. Rep., 26, 11, 1385-1407, 10.1039/b817073h, 19844638
Unusual chemistry in the biosynthesis of the antibiotic chondrochlorens
Publication
Rachid S,
Scharfe M,
Blöcker H,
Weissman K,
Müller R
(2009)
Chem. Biol., 16, 1, 70-81, 10.1016/j.chembiol.2008.11.005, 19171307
Chem. Biol., 16, 1, 70-81, 10.1016/j.chembiol.2008.11.005, 19171307
Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition
Publication
Fu J,
Wenzel S,
Perlova O,
Wang J,
Gross F,
Tang Z,
Yin Y,
Stewart A,
Müller R,
Zhang Y
(2008)
Nucleic Acids Res., 36, 17, 10.1093/nar/gkn499, 18701643
Nucleic Acids Res., 36, 17, 10.1093/nar/gkn499, 18701643
Epothilones - a fascinating family of microtubule stabilizing antitumor agents
Publication
Mulzer J,
Altmann K,
Hofle G,
Müller R,
Prantz K
(2008)
Comptes Rendus Chimie, 11, 11-12, 1336-1368, 10.1016/j.crci.2008.02.005
Comptes Rendus Chimie, 11, 11-12, 1336-1368, 10.1016/j.crci.2008.02.005
Isolation and structure revision of the actin-binding macrolide rhizopodin from Myxococcus stipitatus (Myxobacteria)
Publication
Jansen R,
Steinmetz H,
Sasse F,
Schubert W,
Hagelueken G,
Albrecht S,
Müller R
(2008)
Tetrahedron Lett., 49, 40, 5796-5799, 10.1016/j.tetlet.2008.07.132
Tetrahedron Lett., 49, 40, 5796-5799, 10.1016/j.tetlet.2008.07.132
NtcA-A negative regulator of secondary metabolite biosynthesis in Sorangium cellulosum
Publication
Rachid S,
Gerth K,
Müller R
(2008)
J. Biotechnol., 140, 1-2, 135-142, 10.1016/j.jbiotec.2008.10.010, 19041909
J. Biotechnol., 140, 1-2, 135-142, 10.1016/j.jbiotec.2008.10.010, 19041909
Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester
Publication
Li Y,
Weissman K,
Müller R
(2008)
J. Am. Chem. Soc., 130, 24, 7554-7555, 10.1021/ja8025278, 18498160
J. Am. Chem. Soc., 130, 24, 7554-7555, 10.1021/ja8025278, 18498160
Protein-protein interactions in multienzyme megasynthetases
Publication
Weissman K,
Müller R
(2008)
ChemBioChem, 9, 6, 826-848, 10.1002/cbic.200700751
ChemBioChem, 9, 6, 826-848, 10.1002/cbic.200700751
Epothilones - A fascinating family of microtubule stabilizing antitumor agents
Publication
Mulzer J,
Altmann K,
Höfle G,
Müller R,
Prantz K
(2008)
C. R. Chimie, 11
C. R. Chimie, 11