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Discovery of the Streptoketides by Direct Cloning and Rapid Heterologous Expression of a Cryptic PKS II Gene Cluster from Streptomyces sp. Tü 6314
Publication
Qian Z,
Bruhn T,
D'Agostino P,
Herrmann A,
Haslbeck M,
Antal N,
Fiedler H,
Brack-Werner R,
Gulder T
(2020)
J. Org. Chem., 85, 2, 664-673, 10.1021/acs.joc.9b02741, 31746205
J. Org. Chem., 85, 2, 664-673, 10.1021/acs.joc.9b02741, 31746205
The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase
Publication
Lilic M,
Chen J,
Boyaci H,
Braffman N,
Hubin E,
Herrmann J,
Müller R,
Mooney R,
Landick R,
Darst S,
Campbell E
(2020)
Proc. Natl. Acad. Sci. U.S.A., 10.1073/pnas.2013706117, 33199626
Proc. Natl. Acad. Sci. U.S.A., 10.1073/pnas.2013706117, 33199626
Dual-Seq reveals genome and transcriptome of Caedibacter taeniospiralis, obligate endosymbiont of Paramecium
Publication
Pirritano M,
Zaburannyi N,
Grosser K,
Gasparoni G,
Müller R,
Simon M,
Schrallhammer M
(2020)
Sci. Rep., 10, 1, 10.1038/s41598-020-65894-1, 32546745
Sci. Rep., 10, 1, 10.1038/s41598-020-65894-1, 32546745
How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings-A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish Larvae
Publication
Wagmann L,
Frankenfeld F,
Park Y,
Herrmann J,
Fischmann S,
Westphal F,
Müller R,
Flockerzi V,
Meyer M
(2020)
Frontiers in chemistry, 8, 10.3389/fchem.2020.00539, 32766204
Frontiers in chemistry, 8, 10.3389/fchem.2020.00539, 32766204
Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs
Publication
Li H,
Ranhotra H,
Mani S,
Dvorák Z,
Sokol H,
Müller R
(2020)
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605
The ROK like protein of Myxococcus xanthus DK1622 acts as a pleiotropic transcriptional regulator for secondary metabolism
Publication
Izzat S,
Rachid S,
Ajdidi A,
El-Nakady Y,
Liu X,
Ye B,
Müller R
(2020)
J. Biotechnol., 311, 25-34, 10.1016/j.jbiotec.2020.02.005, 32057784
J. Biotechnol., 311, 25-34, 10.1016/j.jbiotec.2020.02.005, 32057784
Discovery and Comparison of Homogeneous Catalysts in a Standardized HOT‐CAT Screen with Microwave‐Heating and qNMR Analysis: Exploring Catalytic Hydration of Alkynes
Publication
Schreyer M,
Milzarek T,
Wegmann M,
Brunner A,
Hintermann L
(2020)
ChemCatChem, 12, 1, 152-168, 10.1002/cctc.201900456
ChemCatChem, 12, 1, 152-168, 10.1002/cctc.201900456
Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential
Publication
Sib A,
Milzarek T,
Herrmann A,
Oubraham L,
Müller J,
Pichlmair A,
Brack-Werner R,
Gulder T
(2020)
ChemBioChem, 21, 4, 492-495, 10.1002/cbic.201900472, 31448469
ChemBioChem, 21, 4, 492-495, 10.1002/cbic.201900472, 31448469
Myxobakterielle Naturstofffabriken
Publication
Krug D,
Garcia R,
Müller R
(2020)
Biospektrum, 26, 1, 32-36, 10.1007/s12268-020-1334-1
Biospektrum, 26, 1, 32-36, 10.1007/s12268-020-1334-1
Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties
Publication
Mojicevic M,
D'Agostino P,
Pavic A,
Vojnovic S,
Senthamaraikannan R,
Vasiljevic B,
Gulder T,
Nikodinovic-Runic J
(2020)
MicrobiologyOpen, 9, 3, 10.1002/mbo3.986, 31989798
MicrobiologyOpen, 9, 3, 10.1002/mbo3.986, 31989798