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Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism
Publication
Dahlem C,
Siow W,
Lopatniuk M,
Tse W,
Kessler S,
Kirsch S,
Hoppstädter J,
Vollmar A,
Müller R,
Luzhetskyy A,
Bartel K,
Kiemer A
(2020)
Cancers, 12, 5, 10.3390/cancers12051288, 32438733
Cancers, 12, 5, 10.3390/cancers12051288, 32438733
2-Hydroxysorangiadenosine: Structure and Biosynthesis of a Myxobacterial Sesquiterpene-Nucleoside
Publication
Okoth D,
Hug J,
Garcia R,
Spröer C,
Overmann J,
Müller R
(2020)
Molecules (Basel, Switzerland), 25, 11, 10.3390/molecules25112676, 32527018
Molecules (Basel, Switzerland), 25, 11, 10.3390/molecules25112676, 32527018
Heterologous expression of the atypical tetracycline chelocardin reveals the full set of genes required for its biosynthesis
Publication
Lukežic T,
Pikl Š,
Zaburannyi N,
Remškar M,
Petkovic H,
Müller R
(2020)
Microb. Cell Fact., 19, 1, 10.1186/s12934-020-01495-x, 33341113
Microb. Cell Fact., 19, 1, 10.1186/s12934-020-01495-x, 33341113
Anti-Inflammatory Potential of Green Synthesized Silver Nanoparticles of the Soft Coral Nephthea Sp. Supported by Metabolomics Analysis and Docking Studies
Publication
Abdelhafez O,
Ali T,
Fahim J,
Desoukey S,
Ahmed S,
Behery F,
Kamel M,
Gulder T,
Abdelmohsen U
(2020)
Int. J. Nanomedicine, 15, 5345-5360, 10.2147/IJN.S239513, 32801693
Int. J. Nanomedicine, 15, 5345-5360, 10.2147/IJN.S239513, 32801693
Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections
Publication
Schiefer A,
Hübner M,
Krome A,
Lämmer C,
Ehrens A,
Aden T,
Koschel M,
Neufeld H,
Chaverra-Muñoz L,
Jansen R,
Kehraus S,
König G,
Pogorevc D,
Müller R,
Stadler M,
Hüttel S,
Hesterkamp T,
Wagner K,
Pfarr K,
Hoerauf A
(2020)
PLoS Negl. Trop. Dis., 14, 12, 10.1371/journal.pntd.0008930, 33284808
PLoS Negl. Trop. Dis., 14, 12, 10.1371/journal.pntd.0008930, 33284808
Synthetic and Biological Studies on New Urea and Triazole Containing Cystobactamid Derivatives
Publication
Planke T,
Cirnski K,
Herrmann J,
Müller R,
Kirschning A
(2020)
Chem. Eur. J., 26, 19, 4289-4296, 10.1002/chem.201904073, 31834653
Chem. Eur. J., 26, 19, 4289-4296, 10.1002/chem.201904073, 31834653
Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics
Publication
Elgaher W,
Hamed M,
Baumann S,
Herrmann J,
Siebenbürger L,
Krull J,
Cirnski K,
Kirschning A,
Brönstrup M,
Müller R,
Hartmann R
(2020)
Chem. Eur. J., 26, 32, 7219-7225, 10.1002/chem.202000117, 31984562
Chem. Eur. J., 26, 32, 7219-7225, 10.1002/chem.202000117, 31984562
ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli
Publication
Wallenstein A,
Rehm N,
Brinkmann M,
Selle M,
Bossuet-Greif N,
Sauer D,
Bunk B,
Spröer C,
Wami H,
Homburg S,
Bünau R,
König S,
Nougayrède J,
Overmann J,
Oswald E,
Müller R,
Dobrindt U
(2020)
mSphere, 5, 4, 10.1128/mSphere.00591-20, 32669458
mSphere, 5, 4, 10.1128/mSphere.00591-20, 32669458
Discovery of the Streptoketides by Direct Cloning and Rapid Heterologous Expression of a Cryptic PKS II Gene Cluster from Streptomyces sp. Tü 6314
Publication
Qian Z,
Bruhn T,
D'Agostino P,
Herrmann A,
Haslbeck M,
Antal N,
Fiedler H,
Brack-Werner R,
Gulder T
(2020)
J. Org. Chem., 85, 2, 664-673, 10.1021/acs.joc.9b02741, 31746205
J. Org. Chem., 85, 2, 664-673, 10.1021/acs.joc.9b02741, 31746205
The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase
Publication
Lilic M,
Chen J,
Boyaci H,
Braffman N,
Hubin E,
Herrmann J,
Müller R,
Mooney R,
Landick R,
Darst S,
Campbell E
(2020)
Proc. Natl. Acad. Sci. U.S.A., 10.1073/pnas.2013706117, 33199626
Proc. Natl. Acad. Sci. U.S.A., 10.1073/pnas.2013706117, 33199626