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Researchers in HIPS Laboratory

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Searched for "natural products". Displaying results 251 to 260 of 707.

Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead

Publication
Bauman K, Shende V, Chen P, Trivella D, Gulder T, Vellalath S, Romo D, Moore B (2022)
Nat. Chem. Biol., 18, 5, 538-546, 10.1038/s41589-022-00993-w, 35314816

Decoding the diagnostic and therapeutic potential of microbiota using pan-body pan-disease microbiomics

Publication
Schmartz G, Rehner J, Gund M, Keller V, Molano L, Rupf S, Hannig M, Berger T, Flockerzi E, Seitz B, Fleser S, Schmitt-Grohé S, Kalefack S, Zemlin M, Kunz M, Götzinger F, Gevaerd C, Vogt T, Reichrath J, Diehl L, Hecksteden A, Meyer T, Herr C, Gurevich A, Krug D, Hegemann J, Bozhueyuek K, Gulder T, Fu C, Beemelmanns C, Schattenberg J, Kalinina O, Becker A, Unger M, Ludwig N, Seibert M, Stein M, Hanna N, Martin M, Mahfoud F, Krawczyk M, Becker S, Müller R, Bals R, Keller A (2024)
Nat. Commun., 15, 1, 10.1038/s41467-024-52598-7, 39327438

Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins

Publication
Fu C, Liu Y, Walt C, Rasheed S, Bader C, Lukat P, Neuber M, Haeckl F, Blankenfeldt W, Kalinina O, Müller R (2024)
Nat Commun, 15, 1, 10.1038/s41467-024-44953-5, 38278788

Tandem ketone reduction in pepstatin biosynthesis reveals an F420H2-dependent statine pathway

Publication
Mo J, Sikandar A, Zhao H, Bashiri G, Huo L, Empting M, Müller R, Fu C (2025)
Nat Commun, 16, 1, 10.1038/s41467-025-59785-0, 40374670

Towards the sustainable discovery and development of new antibiotics

Publication
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo P, Glaser P, Aigle B, Bode H, Moreira R, Li Y, Luzhetskyy A, Medema M, Pernodet J, Stadler M, Tormo J, Genilloud O, Truman A, Weissman K, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch A, Loretz B, Lehr C, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock L, Gilbert I, Moser H, Müller R (2021)
Nature reviews. Chemistry, 5, 10, 726-749, 10.1038/s41570-021-00313-1, 34426795

Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs

Publication
Li H, Ranhotra H, Mani S, Dvorák Z, Sokol H, Müller R (2020)
Drug Discov. Today, 25, 9, 1575-1579, 10.1016/j.drudis.2020.06.007, 32562605

The ROK like protein of Myxococcus xanthus DK1622 acts as a pleiotropic transcriptional regulator for secondary metabolism

Publication
Izzat S, Rachid S, Ajdidi A, El-Nakady Y, Liu X, Ye B, Müller R (2020)
J. Biotechnol., 311, 25-34, 10.1016/j.jbiotec.2020.02.005, 32057784

Discovery and Comparison of Homogeneous Catalysts in a Standardized HOT‐CAT Screen with Microwave‐Heating and qNMR Analysis: Exploring Catalytic Hydration of Alkynes

Publication
Schreyer M, Milzarek T, Wegmann M, Brunner A, Hintermann L (2020)
ChemCatChem, 12, 1, 152-168, 10.1002/cctc.201900456

Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential

Publication
Sib A, Milzarek T, Herrmann A, Oubraham L, Müller J, Pichlmair A, Brack-Werner R, Gulder T (2020)
ChemBioChem, 21, 4, 492-495, 10.1002/cbic.201900472, 31448469

Myxobakterielle Naturstofffabriken

Publication
Krug D, Garcia R, Müller R (2020)
Biospektrum, 26, 1, 32-36, 10.1007/s12268-020-1334-1