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Production optimization and biosynthesis revision of corallopyronin A, a potent anti-filarial antibiotic
Publication
Pogorevc D,
Panter F,
Schillinger C,
Jansen R,
Wenzel S,
Müller R
(2019)
Metab. Eng., 55, 201-211, 10.1016/j.ymben.2019.07.010, 31340171
Metab. Eng., 55, 201-211, 10.1016/j.ymben.2019.07.010, 31340171
A transposon-based strategy to scale up myxothiazol production in myxobacterial cell factories
Publication
Sandmann A,
Frank B,
Müller R
(2008)
J. Biotechnol., 135, 3, 255-261, 10.1016/j.jbiotec.2008.05.001, 18555551
J. Biotechnol., 135, 3, 255-261, 10.1016/j.jbiotec.2008.05.001, 18555551
Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes
Publication
Kopp M,
Irschik H,
Pradella S,
Müller R
(2005)
ChemBioChem, 6, 7, 1277-1286, 10.1002/cbic.200400459
ChemBioChem, 6, 7, 1277-1286, 10.1002/cbic.200400459
Biosynthesis and Heterologous Production of Vioprolides: Rational Biosynthetic Engineering and Unprecedented 4-Methylazetidinecarboxylic Acid Formation
Publication
Yan F,
Auerbach D,
Chai Y,
Keller L,
Tu Q,
Hüttel S,
Glemser A,
Grab H,
Bach T,
Zhang Y,
Müller R
(2018)
Angew. Chem. Int. Ed. Engl., 57, 28, 8754-8759, 10.1002/anie.201802479, 29694699
Angew. Chem. Int. Ed. Engl., 57, 28, 8754-8759, 10.1002/anie.201802479, 29694699
Deciphering regulatory mechanisms for secondary metabolite production in the myxobacterium Sorangium cellulosum So ce56
Publication
Rachid S,
Gerth K,
Kochems I,
Müller R
(2007)
Mol. Microbiol., 63, 6, 1783-1796, 10.1111/j.1365-2958.2007.05627.x, 17367395
Mol. Microbiol., 63, 6, 1783-1796, 10.1111/j.1365-2958.2007.05627.x, 17367395
In vitro production and purification of isochorismate using a two-enzyme cascade
Publication
Hubrich F,
Müller M,
Andexer J
(2014)
J. Biotechnol., 191, 93-8, 10.1016/j.jbiotec.2014.06.003, 24915130
J. Biotechnol., 191, 93-8, 10.1016/j.jbiotec.2014.06.003, 24915130
Metabolic engineering of Pseudomonas putida for production of docosahexaenoic acid based on a myxobacterial PUFA synthase
Publication
Gemperlein K,
Zipf G,
Bernauer H,
Müller R,
Wenzel S
(2016)
Metab. Eng., 33, 98-108, 10.1016/j.ymben.2015.11.001, 26617065
Metab. Eng., 33, 98-108, 10.1016/j.ymben.2015.11.001, 26617065
Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics
Publication
Lukežic T,
Fayad A,
Bader C,
Harmrolfs K,
Bartuli J,
Groß S,
Lešnik U,
Hennessen F,
Herrmann J,
Pikl Š,
Petkovic H,
Müller R
(2019)
ACS Chem. Biol., 14, 3, 468-477, 10.1021/acschembio.8b01125, 30747520
ACS Chem. Biol., 14, 3, 468-477, 10.1021/acschembio.8b01125, 30747520
Production of a Dibrominated Aromatic Secondary Metabolite by a Planctomycete Implies Complex Interaction with a Macroalgal Host
Publication
Panter F,
Garcia R,
Thewes A,
Zaburannyi N,
Bunk B,
Overmann J,
Gutierrez M,
Krug D,
Müller R
(2019)
ACS Chem. Biol., 14, accepted // 12, 2713-2719, 10.1021/acschembio.9b00641, 31644258
ACS Chem. Biol., 14, accepted // 12, 2713-2719, 10.1021/acschembio.9b00641, 31644258
Direct pathway cloning of the sodorifen biosynthetic gene cluster and recombinant generation of its product in E. coli
Publication
Duell E,
D'Agostino P,
Shapiro N,
Woyke T,
Fuchs T,
Gulder T
(2019)
Microb. Cell Fact., 18, 1, 10.1186/s12934-019-1080-6, 30732610
Microb. Cell Fact., 18, 1, 10.1186/s12934-019-1080-6, 30732610