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Researchers in HIPS Laboratory

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Searched for "drug". Displaying results 681 to 686 of 686.

Dynamic Combinatorial Chemistry Unveils Nsp10 Inhibitors with Antiviral Potential Against SARS-CoV-2

Publication
Jumde R, Jézéquel G, Saramago M, Frank N, Adam S, Cunha M, Bader C, Gunesch A, Köhler N, Johannsen S, Bousis S, Pietschmann T, Matos R, Müller R, Arraiano C, Hirsch A (2024)
Chem. - Eur. J., 10.1002/chem.202403390, 39676060

Innovative zinc-binding inhibitors of Legionella pneumophila ProA reduce collagen and flagellin degradation, TLR5 evasion, and human lung tissue inflammation

Publication
Scheithauer L, Ornago C, Selmar J, Schütz C, Bianchi G, Kiefer A, Haupenthal J, Dellmann A, Huynh D, Zhang R, Blankenfeldt W, Hirsch A, Steinert M (2025)
European journal of medicinal chemistry, 296, 10.1016/j.ejmech.2025.117832, 40479898

Engineering an Artificial Myxopyronin Derivative with Enhanced Metabolic Stability via Mutasynthesis

Publication
Kiefer A, Voltz A, Scherzer D, Reberšek R, Kany A, Prosser G, Neuber M, Reiling N, Hirsch A, Müller R (2025)
, 10.26434/chemrxiv-2025-q4h0n

Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity

Publication
Ropponen H, Bader C, Diamanti E, Illarionov B, Rottmann M, Fischer M, Witschel M, Müller R, Hirsch A (2021)
ChemMedChem, 16, 13, 2089-2093, 10.1002/cmdc.202100067, 33844432

Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model

Publication
Kiefer A, Schütz C, Englisch C, Kolling D, Speicher S, Kany A, Shafiei R, Wadood N, Aljohmani A, Wirschem N, Jumde R, Klein A, Sikandar A, Park Y, Krasteva-Christ G, Yildiz D, Abdelsamie A, Rox K, Köhnke J, Müller R, Bischoff M, Haupenthal J, Hirsch A (2025)
Adv. Sci., 10.1002/advs.202411807, 39973061

Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum

Publication
Kiefer A, Bader C, Held J, Esser A, Rybniker J, Empting M, Müller R, Kazmaier U (2019)
Chem. Eur. J., 25, 37, 8894-8902, 10.1002/chem.201901640, 31012978