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Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform
Publication
Ho D,
Christmann R,
Murgia X,
Rossi C,
Frisch S,
Koch M,
Schaefer U,
Loretz B,
Desmaele D,
Couvreur P,
Lehr C
(2020)
Frontiers in chemistry, 8, 10.3389/fchem.2020.584242, 33195079
Frontiers in chemistry, 8, 10.3389/fchem.2020.584242, 33195079
Saarvienin A - A Novel Glycopeptide with Potent Activity against Drug-resistant Bacteria
Publication
Kaur A,
Guerrero-Garzón J,
Rasheed S,
Zehl M,
Fries F,
Morgenstern B,
Zotchev S,
Müller R
(2025)
Angewandte Chemie (International ed. in English), 10.1002/anie.202425588, 40249031
Angewandte Chemie (International ed. in English), 10.1002/anie.202425588, 40249031
Raman microscopy for cellular investigations--From single cell imaging to drug carrier uptake visualization
Publication
Kann B,
Offerhaus H,
Windbergs M,
Otto C
(2015)
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa
Publication
Meiers J,
Zahorska E,
Röhrig T,
Hauck D,
Wagner S,
Titz A
(2020)
Journal of medicinal chemistry, 63, 20, 11707-11724, 10.1021/acs.jmedchem.0c00856, 32924479
Journal of medicinal chemistry, 63, 20, 11707-11724, 10.1021/acs.jmedchem.0c00856, 32924479
A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1
Publication
van der Vlag R,
Guo H,
Hapko U,
Eleftheriadis N,
Monjas L,
Dekker F,
Hirsch A
(2019)
European journal of medicinal chemistry, 174, 45-55, 10.1016/j.ejmech.2019.04.021, 31026746
European journal of medicinal chemistry, 174, 45-55, 10.1016/j.ejmech.2019.04.021, 31026746
Epistatic Interactions in NS5A of Hepatitis C Virus Suggest Drug Resistance Mechanisms
Publication
Knops E,
Sierra S,
Kalaghatgi P,
Heger E,
Kaiser R,
Kalinina O
(2018)
Genes, 9, 7, 10.3390/genes9070343, 29986475
Genes, 9, 7, 10.3390/genes9070343, 29986475
Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections
Publication
Calvert M,
Jumde V,
Titz A
(2018)
Beilstein journal of organic chemistry, 14, 2607-2617, 10.3762/bjoc.14.239, 30410623
Beilstein journal of organic chemistry, 14, 2607-2617, 10.3762/bjoc.14.239, 30410623
The role of mucus on drug transport and its potential to affect therapeutic outcomes
Publication
Murgia X,
Loretz B,
Hartwig O,
Hittinger M,
Lehr C
(2018)
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
The Non-Mevalonate Pathway to Isoprenoid Biosynthesis: A Potential Source of New Drug Targets
Publication
Hirsch A,
Diederich F
(2008)
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
Combinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization
Publication
Fittler H,
Avrutina O,
Glotzbach B,
Empting M,
Kolmar H
(2013)
Org. Biomol. Chem., 11, 11, 1848-57, 10.1039/c3ob27469a, 23361403
Org. Biomol. Chem., 11, 11, 1848-57, 10.1039/c3ob27469a, 23361403