Jan Schlemmer studied biotechnology at the Hochschule Mannheim where he obtained his bachelor’s degree in 2015 and his master’s degree in 2017. During his studies, he worked as an intern in the biotechnological department of Badan Pengkajian dan Penerapan Teknologi (BPPT) in Jakarta, Indonesia. While working on his bachelor and master thesis, Jan stayed with Prof. Dr. Ian Wheeldon at the University of California, Riverside (UCR) and worked as a visiting graduate researcher in Prof. Dr. Yi Tang’s lab at University of California Los Angeles (UCLA). Since November 2017, he works as a PhD candidate in Prof. Dr. Rolf Müller’s group at HIPS.
His research focuses on the genetic engineering of myxobacterial biosynthetic gene clusters for secondary metabolite production. He is currently working on the assembly and heterologous expression of the NRPS-gene cluster responsible for the production of the peptide antibiotic Myxovalargin. He is interested in engineering the NRPS genes to obtain new and bioactive derivatives. Furthermore, Jan deals with the heterologous expression of the PKS gene cluster involved in the formation of the glycosylated macrolide-antibiotic Disciformycin. The identification and assignment of missing tailoring enzymes to the Disciformycin biosynthesis is one of the fields Jan is especially interested in.