Dr Ravindra P. Jumde


Dr. Ravindra P. Jumde studied Chemical Sciences at the Amravati University (India) and worked as a Project Assistant at National Chemical Laboratory, Pune, India from 2006 to 2008. In 2009 he got Galileo Galilei PhD fellowship to work in the group of Prof. Dario Pini and Dr Alessandro Mandoli at University of Pisa. After completing his PhD in 2012, he first worked as a postdoctoral fellow at University of Pisa and then moved to Institute of Molecular Science and Technology, Milan (ISTM-CNR) in the group of Dr Claudio Evangelisti. From 2015 to 2017 he worked as a senior postdoc at the University of Groningen in Prof. S. Harutyunyan group. In October 2017 he joined Prof. Anna Hirsch group at HIPS and since March 2018 he is a Marie Skłodowska-Curie Researcher at HIPS.


Hit-optimization using target-directed dynamic combinatorial chemistry: Development of inhibitors of the anti-infective target 1-deoxy-D-xylulose-5-phosphate synthase

Jumde R, Guadigni M, Gierse R, Alhayek A, Di Zhu, Hamid Z, Johannsen S, Elgaher W, Neusens P, Nehls C, …, Reiling N, Hirsch A (2021)

Chemical ScienceDOI: 10.1039/D1SC00330E

Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design

Axer A, Jumde R, Adam S, Faust A, Schäfers M, Fobker M, Koehnke J, Hirsch A, Gilmour R (2021)

Chem. Sci. 12 (4): 1286-1294DOI: 10.1039/D0SC04297H


Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics

Grandclaudon C, Birudukota N, Elgaher W, Jumde R, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, …, Hirsch A, Brönstrup M (2020)

European journal of medicinal chemistry 188DOI: 10.1016/j.ejmech.2019.112005

Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach

Konstantinidou M, Magari F, Sutanto F, Haupenthal J, Jumde R, Ünver M, Heine A, Camacho C, Hirsch A, Klebe G, Dömling A (2020)

ChemMedChem 15 (8): 680-684DOI: 10.1002/cmdc.202000024

Validating the 1,2-Difluoro Motif As a Hybrid Bioisostere of CF3 and Et Using Matrix Metalloproteinases As Structural Probes

Erdeljac N, Thiehoff C, Jumde R, Daniliuc C, Höppner S, Faust A, Hirsch A, Gilmour R (2020)

Journal of medicinal chemistry 63 (11): 6225-6237DOI: 10.1021/acs.jmedchem.0c00648


Inverting Small Molecule–Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H→F Bioisosterism

Bentler P, Bergander K, Daniliuc C, Mück-Lichtenfeld C, Jumde R, Hirsch A, Gilmour R (2019)

Angewandte Chemie (International ed. in English) 58 (32): 10990-10994DOI: 10.1002/anie.201905452