Researcher in Laboratory © HIPS

Dr Feng Xie


Feng Xie studied bioengineering from 2004-2008 at Anhui University in China. He received his Doctor's degree in biochemistry and molecular biology at University of Science and Technology of China in 2015. In 2015, he started new research career as a Postdoc at the Institute of Microbiology, Chinese Academy of Sciences. In 2017, he was sponsored by the China and Germany Postdoctoral Exchange Program and became a Postdoc fellow in the group of Professor Rolf Müller at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Germany. In 2019, he continued to work with Professor Müller as a postdoc researcher at the HIPS. Feng Xie's work mainly focuses on the genome mining, pathway characterization and synthetic biology for new active small molecules with state-of-art technologies.


Insights into the biosynthesis of icumazole, unveiling a distinctive family of crotonyl-CoA carboxylase/reductase

Xie F, Kiefer A, Hirsch A, Kalinina O, Fu C, Müller R (2023)

Cell Reports Physical Science 4 (5)DOI: 10.1016/j.xcrp.2023.101394


Stereoselective Syntheses of Deuterated Pipecolic Acids as Tools to Investigate the Stereoselectivity of the Hydroxylase GetF

Neis N, Xie F, Krug D, Zhao H, Siebert A, Binz T, Fu C, Müller R, Kazmaier U (2022)

Liebigs Ann. 2022 (13)DOI: 10.1002/ejoc.202200162


Dual-function chromogenic screening-based CRISPR/Cas9 genome editing system for actinomycetes

Wang Q, Xie F, Tong Y, Habisch R, Yang B, Zhang L, Müller R, Fu C (2020)

Applied Microbiology and Biotechnology 104 (1): 225-239DOI: 10.1007/s00253-019-10223-4


Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro4.4non-8-ene

Fu C, Xie F, Hoffmann J, Wang Q, Bauer A, Brönstrup M, Mahmud T, Müller R (2019)

ChemBioChem 20 (6): 764-769DOI: 10.1002/cbic.201800791