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Dr Eleonora Diamanti

About

Eleonora Diamanti was trained as medicinal chemist and did her Ph.D. with Prof. Piomelli (iit, Genova), working one year with Prof. Aggarwal and his team in Bristol on the total synthesis of a natural product. In 2016, she joined the Hirsch group as a postdoctoral fellow at the University of Groningen and she is currently working at HIPS, focusing on the design and synthesis of anti-infective agents.


2022

Structure-Guided Optimization of Small-Molecule Folate Uptake Inhibitors Targeting the Energy-Coupling Factor Transporters

Kiefer A, Bousis S, Hamed M, Diamanti E, Haupenthal J, Hirsch A (2022)

J. Med. Chem.DOI: 10.1021/acs.jmedchem.1c02114

Bacteriomimetic Liposomes Improve Antibiotic Activity of a Novel Energy-Coupling Factor Transporter Inhibitor

Drost M, Diamanti E, Fuhrmann K, Goes A, Shams A, Haupenthal J, Koch M, Hirsch A, Fuhrmann G (2022)

Pharmaceutics 14 (1)DOI: 10.3390/pharmaceutics14010004

2021

Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class

Diamanti E, Hamed M, Lacour A, Bravo P, Illarionov B, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)

ChemMedChemDOI: 10.1002/cmdc.202100679

Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds

Diamanti E, Setyawati I, Bousis S, Souza P, mojas l, Swier l, Haupenthal J, Gibson P, Volz C, stanek w, …, slotboom d, Hirsch A (2021)

ChemRxivDOI: 10.26434/chemrxiv-2021-xq08b-v2

An efficient way to screen inhibitors of energy-coupling factor (ECF) transporters in bacteria uptake assay

Bousis S, Winkler S, Haupenthal J, Fulco F, Diamanti E, Hirsch A (2021)

ChemRxivDOI: 10.26434/chemrxiv-2021-b50gj

Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity

Ropponen H, Bader C, Diamanti E, Illarionov B, Rottmann M, Fischer M, Witschel M, Müller R, Hirsch A (2021)

ChemMedChem 16 (13): 2089-2093DOI: 10.1002/cmdc.202100067

Assessment of the rules related to gaining activity against Gram-negative bacteria

Ropponen H, Diamanti E, Siemens A, Illarionov B, Haupenthal J, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)

RSC Med. Chem.DOI: 10.1039/D0MD00409J

2020

Discovery of Antibacterial Agents Inhibiting the Energy-Coupling Factor (ECF) Transporters by Structure-Based Virtual Screening

Diamanti E, Setyawati I, Bousis S, mojas l, Swier L, Haupenthal J, Gibson P, Volz C, stanek w, Jaeger m, …, Slotboom D, Hirsch A (2020)

BookDOI: 10.26434/chemrxiv.11728710.v1

2019

Energy-Coupling Factor Transporters as Novel Antimicrobial Targets

Bousis S, Setyawati I, Diamanti E, Slotboom D, Hirsch A (2019)

DOI: 10.1002/ADTP.201800066

2017

DXS as a target for structure-based drug design

Gierse R, Redeem E, Diamanti E, Wrenger C, Groves M, Hirsch A (2017)

Future medicinal chemistry 9 (11): 1277-1294DOI: 10.4155/fmc-2016-0239