Dr Eleonora Diamanti
About
Eleonora Diamanti was trained as medicinal chemist and did her Ph.D. with Prof. Piomelli (iit, Genova), working one year with Prof. Aggarwal and his team in Bristol on the total synthesis of a natural product. In 2016, she joined the Hirsch group as a postdoctoral fellow at the University of Groningen and she is currently working at HIPS, focusing on the design and synthesis of anti-infective agents.
2022
Structure-Guided Optimization of Small-Molecule Folate Uptake Inhibitors Targeting the Energy-Coupling Factor Transporters
Kiefer A, Bousis S, Hamed M, Diamanti E, Haupenthal J, Hirsch A (2022)
J. Med. Chem.DOI: 10.1021/acs.jmedchem.1c02114
Bacteriomimetic Liposomes Improve Antibiotic Activity of a Novel Energy-Coupling Factor Transporter Inhibitor
Drost M, Diamanti E, Fuhrmann K, Goes A, Shams A, Haupenthal J, Koch M, Hirsch A, Fuhrmann G (2022)
Pharmaceutics 14 (1)DOI: 10.3390/pharmaceutics14010004
2021
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
Diamanti E, Hamed M, Lacour A, Bravo P, Illarionov B, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)
ChemMedChemDOI: 10.1002/cmdc.202100679
Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds
Diamanti E, Setyawati I, Bousis S, Souza P, mojas l, Swier l, Haupenthal J, Gibson P, Volz C, stanek w, …, slotboom d, Hirsch A (2021)
ChemRxivDOI: 10.26434/chemrxiv-2021-xq08b-v2
An efficient way to screen inhibitors of energy-coupling factor (ECF) transporters in bacteria uptake assay
Bousis S, Winkler S, Haupenthal J, Fulco F, Diamanti E, Hirsch A (2021)
ChemRxivDOI: 10.26434/chemrxiv-2021-b50gj
Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity
Ropponen H, Bader C, Diamanti E, Illarionov B, Rottmann M, Fischer M, Witschel M, Müller R, Hirsch A (2021)
ChemMedChem 16 (13): 2089-2093DOI: 10.1002/cmdc.202100067
Assessment of the rules related to gaining activity against Gram-negative bacteria
Ropponen H, Diamanti E, Siemens A, Illarionov B, Haupenthal J, Fischer M, Rottmann M, Witschel M, Hirsch A (2021)
RSC Med. Chem.DOI: 10.1039/D0MD00409J
2020
Discovery of Antibacterial Agents Inhibiting the Energy-Coupling Factor (ECF) Transporters by Structure-Based Virtual Screening
Diamanti E, Setyawati I, Bousis S, mojas l, Swier L, Haupenthal J, Gibson P, Volz C, stanek w, Jaeger m, …, Slotboom D, Hirsch A (2020)
BookDOI: 10.26434/chemrxiv.11728710.v1
2019
Energy-Coupling Factor Transporters as Novel Antimicrobial Targets
Bousis S, Setyawati I, Diamanti E, Slotboom D, Hirsch A (2019)
2017
DXS as a target for structure-based drug design
Gierse R, Redeem E, Diamanti E, Wrenger C, Groves M, Hirsch A (2017)
Future medicinal chemistry 9 (11): 1277-1294DOI: 10.4155/fmc-2016-0239