Andreas Klein studied pharmacy at the Saarland University and graduated in 2018. He obtained the degree “Master of Science” for the research in the field of RiPP biosynthesis, within which he focused on the in vitro reconstitution of the Crocagin biosynthesis.
In 2019 he became a registered pharmacist and joined the group of Anna Hirsch in summer 2020.
Since then he has been focusing on establishing an LC-MSMS based assay for the evaluation of novel virulence-inhibitors, especially to tackle Pseudomonas aeruginosa infections.
Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis
Adam S, Zheng D, Klein A, Volz C, Mullen W, Shirran S, Smith B, Kalinina O, Müller R, Koehnke J (2023)
Nature chemistry 15 (4): 560-568DOI: 10.1038/s41557-023-01153-w
Decker H, Dilsen S, Dürre P, Eikmanns B, Eikmanns M, Eggeling L, Elleuche S, Gallert C, Hagen S, Hausmann R, …, Wenzel S, Winter J (2012)
CollectedWorks 1stDOI: 10.1007/978-3-8274-3040-3