Dr Alwin Hartman
About
- Public relations at HIPS: co-responsible for the content of the HIPS website and social media
- Contact person for internal and public events
2020
Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry
Hartman A, Elgaher W, Hertrich N, Andrei S, Ottmann C, Hirsch A (2020)
ACS medicinal chemistry letters 11 (5): 1041-1046DOI: 10.1021/acsmedchemlett.9b00541
Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement
Zielinska A, Savietto A, Sousa Borges A, Martinez D, Berbon M, Roelofsen J, Hartman A, Boer R, van der Klei I, Hirsch A, …, Bramkamp M, Scheffers D (2020)
eLife 9DOI: 10.7554/eLife.57179
Potential Dental Biofilm Inhibitors: Dynamic Combinatorial Chemistry Affords Sugar-Based Molecules that Target Bacterial Glucosyltransferase
Hartman A, Jumde V, Elgaher W, Te Poele E, Dijkhuizen L, Hirsch A (2020)
ChemMedChemDOI: 10.1002/cmdc.202000222
2019
Protein-Templated Dynamic Combinatorial Chemistry: Brief Overview and Experimental Protocol
Hartman A, Gierse R, Hirsch A (2019)
European journal of organic chemistry 2019 (22): 3581-3590DOI: 10.1002/ejoc.201900327
Concepts and Core Principles of Fragment-Based Drug Design
Kirsch P, Hartman A, Hirsch A, Empting M (2019)
Molecules (Basel, Switzerland) 24 (23)DOI: 10.3390/molecules24234309
2018
Lipid-DNAs as Solubilizers of m THPC
Liu Y, de Vries J, Liu Q, Hartman A, Wieland G, Wieczorek S, Börner H, Wiehe A, Buhler E, Stuart M, …, Herrmann A, Hirsch A (2018)
Chem. Eur. J. 24 (4): 798-802DOI: 10.1002/chem.201705206
Donepezil-melatonin hybrids as butyrylcholinesterase inhibitors: Improving binding affinity through varying mode of linking fragments
Lozinska I, Swierczynska A, Moleda Z, Hartman A, Hirsch A, Czarnocki Z (2018)
Archiv der Pharmazie 351 (11)DOI: 10.1002/ardp.201800194
2017
Molecular insight into specific 14-3-3 modulators: Inhibitors and stabilisers of protein-protein interactions of 14-3-3
Hartman A, Hirsch A (2017)
European journal of medicinal chemistry 136DOI: 10.1016/j.ejmech.2017.04.058
Pentapeptide‐rich peptidoglycan at the Bacillus subtilis cell‐division site
Morales Angeles D, Liu Y, Hartman A, Borisova M, Sousa Borges A, Kok N, Beilharz K, veening j, Mayer C, Hirsch A, Scheffers D (2017)
Molecular microbiology 104 (2): 319-333DOI: 10.1111/mmi.13629
2015
Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin
Hartman A, Mondal M, Radeva N, Klebe G, Hirsch A (2015)
International journal of molecular sciences 16 (8): 19184-94DOI: 10.3390/ijms160819184