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Studying Target-Engagement of Anti-Infectives by Solvent-Induced Protein Precipitation and Quantitative Mass Spectrometry
Publikation
Bizzarri L,
Steinbrunn D,
Quennesson T,
Lacour A,
Bianchino G,
Bravo P,
Chaignon P,
Lohse J,
Mäser P,
Seemann M,
van Calenbergh S,
Hirsch A,
Hahne H
(2024)
ACS Infect. Dis., 10, 12, 4087-4102, 10.1021/acsinfecdis.4c00417, 39566904
ACS Infect. Dis., 10, 12, 4087-4102, 10.1021/acsinfecdis.4c00417, 39566904
Biodynamers: self-organization-driven formation of doubly dynamic proteoids
Publikation
Hirsch A,
Buhler E,
Lehn J
(2012)
Journal of the American Chemical Society, 134, 9, 4177-83, 10.1021/ja2099134, 22300496
Journal of the American Chemical Society, 134, 9, 4177-83, 10.1021/ja2099134, 22300496
Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations
Publikation
Tischler M,
Nasu D,
Empting M,
Schmelz S,
Heinz D,
Rottmann P,
Kolmar H,
Buntkowsky G,
Tietze D,
Avrutina O
(2012)
Angewandte Chemie (International ed. in English), 51, 15, 3708-12, 10.1002/anie.201108983, 22374650
Angewandte Chemie (International ed. in English), 51, 15, 3708-12, 10.1002/anie.201108983, 22374650
Total synthesis of (-)-doliculide, structure-activity relationship studies and its binding to F-actin
Publikation
Matcha K,
Madduri A,
Roy S,
Ziegler S,
Waldmann H,
Hirsch A,
Minnaard A
(2012)
ChemBioChem, 13, 17, 2537-48, 10.1002/cbic.201200512, 23129522
ChemBioChem, 13, 17, 2537-48, 10.1002/cbic.201200512, 23129522
'Triazole bridge': disulfide-bond replacement by ruthenium-catalyzed formation of 1,5-disubstituted 1,2,3-triazoles
Publikation
Empting M,
Avrutina O,
Meusinger R,
Fabritz S,
Reinwarth M,
Biesalski M,
Voigt S,
Buntkowsky G,
Kolmar H
(2011)
Angewandte Chemie (International ed. in English), 50, 22, 5207-11, 10.1002/anie.201008142, 21544910
Angewandte Chemie (International ed. in English), 50, 22, 5207-11, 10.1002/anie.201008142, 21544910
Towards click bioconjugations on cube-octameric silsesquioxane scaffolds
Publikation
Fabritz S,
Heyl D,
Bagutski V,
Empting M,
Rikowski E,
Frauendorf H,
Balog I,
Fessner W,
Schneider J,
Avrutina O,
Kolmar H
(2010)
Org. Biomol. Chem., 8, 9, 2212-8, 10.1039/b923393h, 20401398
Org. Biomol. Chem., 8, 9, 2212-8, 10.1039/b923393h, 20401398
Application of copper(I) catalyzed azide-alkyne 3+2 cycloaddition to the synthesis of template-assembled multivalent peptide conjugates
Publikation
Avrutina O,
Empting M,
Fabritz S,
Daneschdar M,
Frauendorf H,
Diederichsen U,
Kolmar H
(2009)
Org. Biomol. Chem., 7, 20, 4177-85, 10.1039/b908261a, 19795056
Org. Biomol. Chem., 7, 20, 4177-85, 10.1039/b908261a, 19795056
SYNTHESIS, ANTI-BRONCHOCONSTRICTIVE, AND ANTIBACTERIAL ACTIVITIES OF SOME NEW 8- SUBSTITUTED-1,3-DIMETHYLXANTHINE DERIVATIVES
Publikation
Elgaher W,
Hayallah A,
Salem O,
Abdel Alim A
(2009)
Bulletin of Pharmaceutical Sciences. Assiut, 32, 1, 153-187, 10.21608/BFSA.2009.63355
Bulletin of Pharmaceutical Sciences. Assiut, 32, 1, 153-187, 10.21608/BFSA.2009.63355
Bioconjugates to specifically render inhibitors water-soluble
Publikation
Hirsch A,
Diederich F,
Antonietti M,
Börner H
(2009)
Soft Matter, 6, 1, 88-91, 10.1039/B915928B
Soft Matter, 6, 1, 88-91, 10.1039/B915928B
Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis
Publikation
Hirsch A,
Alphey M,
Lauw S,
Seet M,
Barandun L,
Eisenreich W,
Rohdich F,
Hunter W,
Bacher A,
Diederich F
(2008)
Organic & biomolecular chemistry, 6, 15, 2719-30, 10.1039/b804375b, 18633530
Organic & biomolecular chemistry, 6, 15, 2719-30, 10.1039/b804375b, 18633530