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Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors
Publikation
Hüsecken K,
Hinsberger S,
Elgaher W,
Haupenthal J,
Hartmann R
(2014)
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Future medicinal chemistry, 6, 14, 1551-65, 10.4155/fmc.14.105, 25367390
Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids
Publikation
Elgaher W,
Fruth M,
Groh M,
Haupenthal J,
Hartmann R
(2013)
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
RSC Adv, 4, 5, 2177-2194, 10.1039/C3RA45820B
New Theophylline Derivatives
Publikation
Elgaher W
(2011)
Book
Book
Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities
Publikation
Hayallah A,
Elgaher W,
Salem O,
Alim A
(2011)
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publikation
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publikation
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publikation
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Publikation
Konstantinovic J,
Kany A,
Alhayek A,
Abdelsamie A,
Sikandar A,
Voos K,
Yao Y,
Andreas A,
Shafiei R,
Loretz B,
Schönauer E,
Bals R,
Brandstetter H,
Hartmann R,
Ducho C,
Lehr C,
Beisswenger C,
Müller R,
Rox K,
Haupenthal J,
Hirsch A
(2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials
Publikation
Walesch S,
Birkelbach J,
Jézéquel G,
Haeckl F,
Hegemann J,
Hesterkamp T,
Hirsch A,
Hammann P,
Müller R
(2023)
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
Point mutations in the ygiV promoter region lead to cystobactamid resistance and reduced virulence in E. coli
Publikation
Müller R,
Risch T,
Kolling D,
Mostert D,
Seedorf T,
Heimann D,
Kohnhäuser D,
Deschner F,
Fries F,
Solga D,
Hilgers J,
Dastbaz J,
Hirsch A,
Brönstrup M,
Kirschning A,
Herrmann J,
Sieber S
(2024)
Book, 10.21203/rs.3.rs-3751821/v1
Book, 10.21203/rs.3.rs-3751821/v1