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Tobramycin crosslinking improves the colloidal stability of arginine chitosan biodynamers for safe and efficient siRNA delivery
Publikation
Liu Y,
Biesel A,
Kamal M,
Latta L,
Loretz B,
Hirsch A,
Lee S,
Lehr C
(2025)
Int. J. Biol. Macromol., 311, Pt 1, 10.1016/j.ijbiomac.2025.143420, 40274164
Int. J. Biol. Macromol., 311, Pt 1, 10.1016/j.ijbiomac.2025.143420, 40274164
Domain adaptable language modeling of chemical compounds identifies potent pathoblockers for Pseudomonas aeruginosa
Publikation
Kallergis G,
Asgari E,
Empting M,
Hirsch A,
Klawonn F,
McHardy A
(2025)
Commun. Chem., 8, 1, 10.1038/s42004-025-01484-4, 40216964
Commun. Chem., 8, 1, 10.1038/s42004-025-01484-4, 40216964
Modular synthetic routes to biologically active indoles from lignin
Publikation
Castillo-Garcia A,
Haupenthal J,
Hirsch A,
Barta K
(2025)
Green Chem., 27, 25, 7506-7512, 10.1039/d5gc01003a, 40510740
Green Chem., 27, 25, 7506-7512, 10.1039/d5gc01003a, 40510740
Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity
Publikation
Braun-Cornejo M,
Platteschorre M,
Vries V,
Bravo P,
Sonawane V,
Hamed M,
Haupenthal J,
Reiling N,
Rottmann M,
Piet D,
Maas P,
Diamanti E,
Hirsch A
(2025)
JACS Au, 5, 3, 1146-1156, 10.1021/jacsau.4c00935, 40151263
JACS Au, 5, 3, 1146-1156, 10.1021/jacsau.4c00935, 40151263
PHIP-label: parahydrogen-induced polarization in propargylglycine-containing synthetic oligopeptides
Publikation
Körner M,
Sauer G,
Heil A,
Nasu D,
Empting M,
Tietze D,
Voigt S,
Weidler H,
Gutmann T,
Avrutina O,
Kolmar H,
Ratajczyk T,
Buntkowsky G
(2013)
Chemical communications (Cambridge, England), 49, 71, 7839-41, 10.1039/c3cc43978j, 23887355
Chemical communications (Cambridge, England), 49, 71, 7839-41, 10.1039/c3cc43978j, 23887355
Total synthesis, stereochemical elucidation and biological evaluation of Ac 2 SGL; a 1,3-methyl branched sulfoglycolipid from Mycobacterium tuberculosis
Publikation
Geerdink D,
Horst B,
Lepore M,
Mori L,
Puzo G,
Hirsch A,
Gilleron M,
Libero G,
Minnaard A
(2013)
, 10.1039/C2SC21620E
, 10.1039/C2SC21620E
Imidazole- and Benzimidazole-Based Inhibitors of the Kinase IspE: Targeting the Substrate-Binding Site and the Triphosphate-Binding Loop of the ATP Site
Publikation
Mombelli P,
Le Chapelain C,
Munzinger N,
Joliat E,
Illarionov B,
Schweizer W,
Hirsch A,
Fischer M,
Bacher A,
Diederich F
(2013)
, 10.1002/EJOC.201201467
, 10.1002/EJOC.201201467
The isoprenoid-precursor dependence of Plasmodium spp
Publikation
van der Meer J,
Hirsch A
(2012)
Natural product reports, 29, 7, 721-8, 10.1039/c2np20013a, 22555616
Natural product reports, 29, 7, 721-8, 10.1039/c2np20013a, 22555616
Metal-ion-induced shape switching: Stereoselective formation of a dinuclear Hg(II) double helicate from a hydrazonobis(acylhydrazone) ligand
Publikation
Schaeffer G,
Harrowfield J,
Lehn J,
Hirsch A
(2012)
, 10.1016/J.POLY.2012.04.013
, 10.1016/J.POLY.2012.04.013
Exploring the Ribose Sub-Pocket of the Substrate-Binding Site in Escherichia coli IspE: Structure-Based Design, Synthesis, and Biological Evaluation of Cytosines and Cytosine Analogues
Publikation
Schütz A,
Osawa S,
Mathis J,
Hirsch A,
Bernet B,
Illarionov B,
Fischer M,
Bacher A,
Diederich F
(2012)
, 10.1002/EJOC.201200296
, 10.1002/EJOC.201200296