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Generation of Semi-Synthetic Shark IgNAR Single-Domain Antibody Libraries
Publikation
Grzeschik J,
Könning D,
Hinz S,
Krah S,
Schröter C,
Empting M,
Kolmar H,
Zielonka S
(2018)
Methods in molecular biology (Clifton, N.J.), 1701, 147-167, 10.1007/978-1-4939-7447-4_8, 29116504
Methods in molecular biology (Clifton, N.J.), 1701, 147-167, 10.1007/978-1-4939-7447-4_8, 29116504
Donepezil-melatonin hybrids as butyrylcholinesterase inhibitors: Improving binding affinity through varying mode of linking fragments
Publikation
Lozinska I,
Swierczynska A,
Moleda Z,
Hartman A,
Hirsch A,
Czarnocki Z
(2018)
Archiv der Pharmazie, 351, 11, 10.1002/ardp.201800194, 30290008
Archiv der Pharmazie, 351, 11, 10.1002/ardp.201800194, 30290008
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds
Publikation
Zender M,
Witzgall F,
Drees S,
Weidel E,
Maurer C,
Fetzner S,
Blankenfeldt W,
Empting M,
Hartmann R
(2016)
ACS chemical biology, 10.1021/acschembio.6b00156, 27082157
ACS chemical biology, 10.1021/acschembio.6b00156, 27082157
Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors
Publikation
Elgaher W,
Sharma K,
Haupenthal J,
Saladini F,
Pires M,
Real E,
Mely Y,
Hartmann R
(2016)
Journal of medicinal chemistry, 10.1021/acs.jmedchem.6b00730, 27339173
Journal of medicinal chemistry, 10.1021/acs.jmedchem.6b00730, 27339173
Structure-Activity Relationships of 2-Sufonylpyrimidines as Quorum-Sensing Inhibitors to Tackle Biofilm Formation and eDNA Release of Pseudomonas aeruginosa
Publikation
Thomann A,
Brengel C,
Börger C,
Kail D,
Steinbach A,
Empting M,
Hartmann R
(2016)
ChemMedChem, 11, 22, 2522-2533, 10.1002/cmdc.201600419, 27731921
ChemMedChem, 11, 22, 2522-2533, 10.1002/cmdc.201600419, 27731921
Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site
Publikation
Masini T,
Birkaya B,
van Dijk S,
Mondal M,
Hekelaar J,
Jäger M,
van Terwisscha Scheltinga A,
Patel M,
Hirsch A,
Moman E
(2016)
Journal of enzyme inhibition and medicinal chemistry, 31, sup4, 170-175, 10.1080/14756366.2016.1201812, 27435185
Journal of enzyme inhibition and medicinal chemistry, 31, sup4, 170-175, 10.1080/14756366.2016.1201812, 27435185
Synthesis and Anticonvulsant Activity of Menthyl γ-Aminobutyrate
Publikation
Nesterkina M,
Kravchenko I
(2016)
Chem Nat Compd, 52, 2, 237-239, 10.1007/s10600-016-1604-9
Chem Nat Compd, 52, 2, 237-239, 10.1007/s10600-016-1604-9
Synthesis and Pharmacological Properties of Novel Esters Based on Monocyclic Terpenes and GABA
Publikation
Nesterkina M,
Kravchenko I
(2016)
Pharmaceuticals (Basel, Switzerland), 9, 2, 10.3390/ph9020032, 27304960
Pharmaceuticals (Basel, Switzerland), 9, 2, 10.3390/ph9020032, 27304960
Analgesic Activity of Novel GABA Esters after Transdermal Delivery
Publikation
Nesterkina M,
Kravchenko I
(2016)
Nat. Prod. Commun., 11, 10, 10.1177/1934578X1601101001
Nat. Prod. Commun., 11, 10, 10.1177/1934578X1601101001
Single-domain antibodies for biomedical applications
Publikation
Krah S,
Schröter C,
Zielonka S,
Empting M,
Valldorf B,
Kolmar H
(2016)
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147
Immunopharmacol. Immunotoxicol., 38, 1, 21-8, 10.3109/08923973.2015.1102934, 26551147