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Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier
Publikation
Abdallah M,
Hamed M,
Frakolaki E,
Katsamakas S,
Vassilaki N,
Bartenschlager R,
Zoidis G,
Hirsch A,
Abdel-Halim M,
Abadi A
(2021)
European journal of medicinal chemistry, 10.1016/j.ejmech.2021.114034
European journal of medicinal chemistry, 10.1016/j.ejmech.2021.114034
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
Publikation
Diamanti E,
Hamed M,
Lacour A,
Bravo P,
Illarionov B,
Fischer M,
Rottmann M,
Witschel M,
Hirsch A
(2021)
ChemMedChem, 10.1002/cmdc.202100679, 34918860
ChemMedChem, 10.1002/cmdc.202100679, 34918860
Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH) (ChemMedChem 8/2021)
Publikation
Voos K,
Schönauer E,
Alhayek A,
Haupenthal J,
Andreas A,
Müller R,
Hartmann R,
Brandstetter H,
Hirsch A,
Ducho C
(2021)
ChemMedChem, 16, 8, 1198-1198, 10.1002/cmdc.202100229
ChemMedChem, 16, 8, 1198-1198, 10.1002/cmdc.202100229
Novel (‒)-carvone derivatives as potential anticonvulsant and analgesic agents
Publikation
Nesterkina M,
Barbalat D,
Konovalova I,
Shishkina S,
Atakay M,
Salih B,
Kravchenko I
(2021)
Natural product research, 35, 23, 4978-4987, 10.1080/14786419.2020.1756804, 32336164
Natural product research, 35, 23, 4978-4987, 10.1080/14786419.2020.1756804, 32336164
“Clicking“ fragment leads to novel dual-binding cholinesterase inhibitors
Publikation
Moleda Z,
Zawadzka A,
Czarnocki Z,
Monjas L,
Hirsch A,
Budzianowski A,
Maurin J
(2021)
Bioorg Med Chem, 10.1016/j.bmc.2021.116269
Bioorg Med Chem, 10.1016/j.bmc.2021.116269
Design, synthesis, and biological evaluation of novel benzimidazole derivatives as sphingosine kinase 1 inhibitor
Publikation
Khairat S,
Omar M,
Ragab F,
Roy S,
Turab Naqvi A,
Abdelsamie A,
Hirsch A,
Galal S,
Hassan M,
El Diwani H
(2021)
Archiv der Pharmazie, 354, 9, 10.1002/ardp.202100080, 34128259
Archiv der Pharmazie, 354, 9, 10.1002/ardp.202100080, 34128259
1st Spring Virtual Meeting on Medicinal Chemistry
Publikation
Sousa M,
Marques M,
Faustino M
(2021)
Chemistry Proceedings, 4, 1, 10.3390/chemproc2021004001
Chemistry Proceedings, 4, 1, 10.3390/chemproc2021004001
Synthesis and pharmacological evaluation of novel naphthoquinone derivatives containing 1,2,4-triazine and 1,2,4-triazole moieties of methylene blue on the surface of a "core–shell" type catalyst for the Fenton system
Publikation
Polish N,
Nesterkina M,
Protunkevych M,
Karkhut A,
Marintsova N,
Polovkovych S,
IKravchenko I,
Voskoboinik O,
Kovalenko S,
Karpenko O
(2021)
Vopr. Khim. Khim. Tekhnol., 5, 97-104, 10.32434/0321-4095-2021-138-5-97-104
Vopr. Khim. Khim. Tekhnol., 5, 97-104, 10.32434/0321-4095-2021-138-5-97-104
Simultaneous Complexation and Microextraction Using Verbenone Hydrazone as the Ligand with Slotted Quartz Tube-Flame Atomic Absorption Spectrometry (FAAS) for the Sensitive Determination of Copper
Publikation
Özzeybek G,
Borahan T,
Nesterkina M,
Kravchenko I,
Bakirdere S
(2021)
Analytical letters, 54, 14, 2376-2386, 10.1080/00032719.2020.1866594
Analytical letters, 54, 14, 2376-2386, 10.1080/00032719.2020.1866594
Unveiling Adatoms in On-Surface Reactions: Combining Scanning Probe Microscopy with van't Hoff Plots
Publikation
Moreno-López J,
Pérez Paz A,
Gottardi S,
Solianyk L,
Li J,
Monjas L,
Hirsch A,
Mowbray D,
Stöhr M
(2021)
The journal of physical chemistry. C, Nanomaterials and interfaces, 125, 18, 9847-9854, 10.1021/acs.jpcc.1c03134, 34276856
The journal of physical chemistry. C, Nanomaterials and interfaces, 125, 18, 9847-9854, 10.1021/acs.jpcc.1c03134, 34276856