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Gesucht nach "drug". Zeige Ergebnisse 421 bis 430 von 675.

Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents

Publikation
Castoldi A, Empting M, Rossi C, Mayr K, Dersch P, Hartmann R, Müller R, Gordon S, Lehr C (2018)
Pharm Res, 36, 1, 10.1007/s11095-018-2521-3, 30519925

Proteoid biodynamers for safe mRNA transfection via pH-responsive nanorods enabling endosomal escape

Publikation
Lee S, Nasr S, Rasheed S, Liu Y, Hartwig O, Kaya C, Boese A, Koch M, Herrmann J, Müller R, Loretz B, Buhler E, Hirsch A, Lehr C (2022)
Journal of controlled release : official journal of the Controlled Release Society, 353, 915-929, 10.1016/j.jconrel.2022.12.018, 36521693

An Outer Membrane Vesicle-Based Permeation Assay (OMPA) for Assessing Bacterial Bioavailability

Publikation
Richter R, Kamal M, Koch M, Niebuur B, Huber A, Goes A, Volz C, Vergalli J, Kraus T, Müller R, Schneider-Daum N, Fuhrmann G, Pagès J, Lehr C (2022)
Advanced healthcare materials, 11, 5, 10.1002/adhm.202101180, 34614289

Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections

Publikation
Ho D, Murgia X, Rossi C, Christmann R, Hüfner de Mello Martins A, Koch M, Andreas A, Herrmann J, Müller R, Empting M, Hartmann R, Desmaele D, Loretz B, Couvreur P, Lehr C (2020)
Angewandte Chemie (International ed. in English), 10.1002/anie.202001407, 32243047

Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity

Publikation
Abdelsamie A, Hamed M, Schütz C, Röhrig T, Kany A, Schmelz S, Blankenfeldt W, Hirsch A, Hartmann R, Empting M (2024)
Eur. J. Med. Chem., 276, 10.1016/j.ejmech.2024.116685, 39042991

Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies

Publikation
Della Volpe S, Nasti R, Queirolo M, Unver M, Jumde V, Dömling A, Vasile F, Potenza D, Ambrosio F, Costa G, Alcaro S, Zucal C, Provenzani A, Di Giacomo M, Rossi D, Hirsch A, Collina S (2019)
ACS Med. Chem. Lett., 10, 4, 615-620, 10.1021/acsmedchemlett.8b00600, 30996806

In-depth Profiling of MvfR-Regulated Small Molecules in Pseudomonas aeruginosa after Quorum Sensing Inhibitor Treatment

Publikation
Allegretta G, Maurer C, Eberhard J, Maura D, Hartmann R, Rahme L, Empting M (2017)
Frontiers in microbiology, 8, 10.3389/fmicb.2017.00924, 28596760

Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections

Publikation
Thomann A, Mello Martins A, Brengel C, Empting M, Hartmann R (2016)
ACS chemical biology, 11, 5, 1279-86, 10.1021/acschembio.6b00117, 26882081

Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa

Publikation
Sahner J, Empting M, Kamal A, Weidel E, Groh M, Börger C, Hartmann R (2015)
European journal of medicinal chemistry, 96, 14-21, 10.1016/j.ejmech.2015.04.007, 25874327

From in vitro to in cellulo: structure-activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa

Publikation
Storz M, Allegretta G, Kirsch B, Empting M, Hartmann R (2014)
Organic & biomolecular chemistry, 12, 32, 6094-104, 10.1039/c4ob00707g, 24909330