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Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs
Publikation
Nasti R,
Rossi D,
Amadio M,
Pascale A,
Unver M,
Hirsch A,
Collina S
(2017)
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Journal of medicinal chemistry, 60, 20, 8257-8267, 10.1021/acs.jmedchem.6b01871, 28587461
Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles
Publikation
Guillot A,
Couffin A,
Sejean X,
Navarro F,
Limberger M,
Lehr C
(2015)
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Pharmaceutical research, 32, 12, 3999-4009, 10.1007/s11095-015-1761-8
Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models
Publikation
Hittinger M,
Juntke J,
Kletting S,
Schneider-Daum N,
de Souza Carvalho C,
Lehr C
(2015)
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Advanced Drug Delivery Reviews, 85, 44-56, 10.1016/j.addr.2014.10.011, 25453270
Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique
Publikation
Bur M,
Huwer H,
Muys L,
Lehr C
(2010)
Journal of aerosol medicine and pulmonary drug delivery, 23, 3, 119-27, 10.1089/jamp.2009.0757, 20073555
Journal of aerosol medicine and pulmonary drug delivery, 23, 3, 119-27, 10.1089/jamp.2009.0757, 20073555
Facile Production of the Pseudomonas aeruginosa Virulence Factor LasB in E. coli for Structure-Based Drug Design
Publikation
Kolling D,
Haupenthal J,
Hirsch A,
Köhnke J
(2023)
ChemBioChem, 10.1002/cbic.202300185, 37195753
ChemBioChem, 10.1002/cbic.202300185, 37195753
Models using native tracheobronchial mucus in the context of pulmonary drug delivery research: Composition, structure and barrier properties
Publikation
Huck B,
Murgia X,
Frisch S,
Hittinger M,
Hidalgo A,
Loretz B,
Lehr C
(2022)
Advanced Drug Delivery Reviews, 183, 10.1016/j.addr.2022.114141, 35149123
Advanced Drug Delivery Reviews, 183, 10.1016/j.addr.2022.114141, 35149123
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro
Publikation
Horstmann J,
Thorn C,
Carius P,
Graef F,
Murgia X,
Souza Carvalho-Wodarz C,
Lehr C
(2021)
Frontiers in Bioengineering and Biotechnology, 9, 10.3389/fbioe.2021.643491, 33968912
Frontiers in Bioengineering and Biotechnology, 9, 10.3389/fbioe.2021.643491, 33968912
A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
Publikation
Carius P,
Jungmann A,
Bechtel M,
Grißmer A,
Boese A,
Gasparoni G,
Salhab A,
Seipelt R,
Urbschat K,
Richter C,
Meier C,
Bojkova D,
Cinatl J,
Walter J,
Schneider-Daum N,
Lehr C
(2023)
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Drug delivery to the inflamed intestinal mucosa- targeting technologies and human cell culture models for better therapies of IBD
Publikation
Olga H,
Shetab Boushehri Maryam A,
Shalaby Karim S,
Brigitta L,
Alf L,
Claus-Michael L
(2021)
Advanced Drug Delivery Reviews, 10.1016/j.addr.2021.113828, 34157320
Advanced Drug Delivery Reviews, 10.1016/j.addr.2021.113828, 34157320
Carrier interactions with the biological barriers of the lung: Advanced in vitro models and challenges for pulmonary drug delivery
Publikation
de Souza Carvalho C,
Daum N,
Lehr C
(2014)
Advanced Drug Delivery Reviews, 75, 129-140, 10.1016/j.addr.2014.05.014, 24880145
Advanced Drug Delivery Reviews, 75, 129-140, 10.1016/j.addr.2014.05.014, 24880145