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A shift of dynamic equilibrium between the KIT active and inactive states causes drug resistance
Publikation
Srikakulam S,
Bastys T,
Kalinina O
(2020)
Proteins, 10.1002/prot.25963, 32530065
Proteins, 10.1002/prot.25963, 32530065
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery**
Publikation
Afanasenko A,
Wu X,
Santi A,
Elgaher W,
Kany A,
Shafiei R,
Schulze M,
Schulz T,
Haupenthal J,
Hirsch A,
Barta K
(2024)
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 136, 4, 10.1002/ange.202308131
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 136, 4, 10.1002/ange.202308131
Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery
Publikation
Afanasenko A,
Wu X,
Santi A,
Elgaher W,
Kany A,
Shafiei R,
Schulze M,
Schulz T,
Haupenthal J,
Hirsch A,
Barta K
(2023)
Angew. Chem. Int. Ed., 10.1002/anie.202308131, 37840425
Angew. Chem. Int. Ed., 10.1002/anie.202308131, 37840425
Expression and characterization of pantothenate energy-coupling factor transporters as an anti-infective drug target
Publikation
Shams A,
Bousis S,
Diamanti E,
Elgaher W,
Zeimetz L,
Haupenthal J,
slotboom d,
Hirsch A
(2024)
Protein Sci., 33, 11, 10.1002/pro.5195, 39473025
Protein Sci., 33, 11, 10.1002/pro.5195, 39473025
Cell and tissue-based in vitro models for improving the development of oral inhalation drug products
Publikation
Hittinger M,
Schneider-Daum N,
Lehr C
(2017)
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
European Journal of Pharmaceutics and Biopharmaceutics, 118, 73-78, 10.1016/j.ejpb.2017.02.019
The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery
Publikation
Sommer R,
Wagner S,
Varrot A,
Nycholat C,
Khaledi A,
Häussler S,
Paulson J,
Imberty A,
Titz A
(2016)
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
Chem Sci, 7, 8, 4990-5001, 10.1039/c6sc00696e, 30155149
In situ drug release monitoring with a fiber-optic system: Overcoming matrix interferences using derivative spectrophotometry
Publikation
Guillot A,
Limberge M,
Krämer J,
Lehr C
(2013)
Dissolution Technologies, 20, 2, 15-19
Dissolution Technologies, 20, 2, 15-19
The synergistic effect of chlorotoxin-mApoE in boosting drug-loaded liposomes across the BBB
Publikation
Formicola B,
Dal Magro R,
Montefusco-Pereira C,
Lehr C,
Koch M,
Russo L,
Grasso G,
Deriu M,
Danani A,
Bourdoulous S,
Re F
(2019)
Journal of nanobiotechnology, 17, 1, 10.1186/s12951-019-0546-3, 31711496
Journal of nanobiotechnology, 17, 1, 10.1186/s12951-019-0546-3, 31711496
A stretchable human lung‐on‐chip model of alveolar inflammation for evaluating anti‐inflammatory drug response
Publikation
Richter C,
Latta L,
Harig D,
Carius P,
Stucki J,
Hobi N,
Hugi A,
Schumacher P,
Krebs T,
Gamrekeli A,
Stöckle F,
Urbschat K,
Montalvo G,
Lautenschläger F,
Loretz B,
Hidalgo A,
Schneider-Daum N,
Lehr C
(2024)
Bioengineering & Transla Med, 10.1002/btm2.10715
Bioengineering & Transla Med, 10.1002/btm2.10715
3D printed tablets loaded with polymeric nanocapsules: An innovative approach to produce customized drug delivery systems
Publikation
Beck R,
Chaves P,
Goyanes A,
Vukosavljevic B,
Buanz A,
Windbergs M,
Basit A,
Gaisford S
(2017)
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328
International journal of pharmaceutics, 528, 1-2, 268-279, 10.1016/j.ijpharm.2017.05.074, 28583328