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Antibiotic resistance and tolerance: What can drug delivery do against this global threat?
Publikation
Aparicio-Blanco J,
Vishwakarma N,
Lehr C,
Prestidge C,
Thomas N,
Roberts R,
Thorn C,
Melero A
(2024)
Drug delivery and translational research, 10.1007/s13346-023-01513-6, 38341386
Drug delivery and translational research, 10.1007/s13346-023-01513-6, 38341386
Epistatic Interactions in NS5A of Hepatitis C Virus Suggest Drug Resistance Mechanisms
Publikation
Knops E,
Sierra S,
Kalaghatgi P,
Heger E,
Kaiser R,
Kalinina O
(2018)
Genes, 9, 7, 10.3390/genes9070343, 29986475
Genes, 9, 7, 10.3390/genes9070343, 29986475
Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections
Publikation
Calvert M,
Jumde V,
Titz A
(2018)
Beilstein journal of organic chemistry, 14, 2607-2617, 10.3762/bjoc.14.239, 30410623
Beilstein journal of organic chemistry, 14, 2607-2617, 10.3762/bjoc.14.239, 30410623
The role of mucus on drug transport and its potential to affect therapeutic outcomes
Publikation
Murgia X,
Loretz B,
Hartwig O,
Hittinger M,
Lehr C
(2018)
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Advanced Drug Delivery Reviews, 124, 82-97, 10.1016/j.addr.2017.10.009, 29106910
Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa
Publikation
Meiers J,
Zahorska E,
Röhrig T,
Hauck D,
Wagner S,
Titz A
(2020)
Journal of medicinal chemistry, 63, 20, 11707-11724, 10.1021/acs.jmedchem.0c00856, 32924479
Journal of medicinal chemistry, 63, 20, 11707-11724, 10.1021/acs.jmedchem.0c00856, 32924479
A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1
Publikation
van der Vlag R,
Guo H,
Hapko U,
Eleftheriadis N,
Monjas L,
Dekker F,
Hirsch A
(2019)
European journal of medicinal chemistry, 174, 45-55, 10.1016/j.ejmech.2019.04.021, 31026746
European journal of medicinal chemistry, 174, 45-55, 10.1016/j.ejmech.2019.04.021, 31026746
Raman microscopy for cellular investigations--From single cell imaging to drug carrier uptake visualization
Publikation
Kann B,
Offerhaus H,
Windbergs M,
Otto C
(2015)
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
Advanced Drug Delivery Reviews, 89, 71-90, 10.1016/j.addr.2015.02.006, 25728764
The Non-Mevalonate Pathway to Isoprenoid Biosynthesis: A Potential Source of New Drug Targets
Publikation
Hirsch A,
Diederich F
(2008)
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
CHIMIA, 62, 4, 226-230, 10.2533/chimia.2008.226
Consistent Prediction of Mutation Effect on Drug Binding in HIV-1 Protease Using Alchemical Calculations
Publikation
Bastys T,
Gapsys V,
Doncheva N,
Kaiser R,
Groot B,
Kalinina O
(2018)
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
Journal of chemical theory and computation, 14, 7, 3397-3408, 10.1021/acs.jctc.7b01109, 29847122
In vitro models for evaluating safety and efficacy of novel technologies for skin drug delivery
Publikation
Planz V,
Lehr C,
Windbergs M
(2016)
Journal of Controlled Release, 242, 89-104, 10.1016/j.jconrel.2016.09.002
Journal of Controlled Release, 242, 89-104, 10.1016/j.jconrel.2016.09.002