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Spray drying of a zinc complexing agent for inhalation therapy of pulmonary fibrosis
Publikation
Stella J,
Abdelaal M,
Kamal M,
Shehu K,
Alhayek A,
Haupenthal J,
Hirsch A,
Schneider M
(2024)
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 202, 10.1016/j.ejps.2024.106891, 39233259
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 202, 10.1016/j.ejps.2024.106891, 39233259
Targeting Plasmodium falciparum IspD in the Methyl-d-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity
Publikation
Willocx D,
Bizzarri L,
Alhayek A,
Kannan D,
Bravo P,
Illarionov B,
Rox K,
Lohse J,
Fischer M,
Kany A,
Hahne H,
Rottmann M,
Witschel M,
Odom John A,
Hamed M,
Diamanti E,
Hirsch A
(2024)
Journal of medicinal chemistry, 67, 19, 17070-17086, 10.1021/acs.jmedchem.4c00212, 39303294
Journal of medicinal chemistry, 67, 19, 17070-17086, 10.1021/acs.jmedchem.4c00212, 39303294
Integral Solvent-Induced Protein Precipitation for Target-Engagement Studies in Plasmodium falciparum
Publikation
Bravo P,
Bizzarri L,
Steinbrunn D,
Lohse J,
Hirsch A,
Mäser P,
Rottmann M,
Hahne H
(2024)
ACS Infect. Dis., 10, 12, 4073-4086, 10.1021/acsinfecdis.4c00418, 39631773
ACS Infect. Dis., 10, 12, 4073-4086, 10.1021/acsinfecdis.4c00418, 39631773
Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT
Publikation
Exapicheidou I,
Shams A,
Ibrahim H,
Tsarenko A,
Backenköhler M,
Hamed M,
Diamanti E,
Volkamer A,
Slotboom D,
Hirsch A
(2024)
Chem. Commun., 60, 7, 870-873, 10.1039/D3CC04738E, 38164786
Chem. Commun., 60, 7, 870-873, 10.1039/D3CC04738E, 38164786
Repellent activity of monoterpenoid esters with neurotransmitter amino acids against yellow fever mosquito, Aedes aegypti
Publikation
Nesterkina M,
Bernier U,
Tabanca N,
Kravchenko I
(2018)
Open Chemistry, 16, 1, 95-98, 10.1515/chem-2018-0015
Open Chemistry, 16, 1, 95-98, 10.1515/chem-2018-0015
Trendbericht Biochemie 2017: Proteinvermittelte dynamische kombinatorische Chemie
Publikation
Hirsch A
(2018)
Nachr. Chem., 66, 3, 281-283, 10.1002/nadc.20184071734
Nachr. Chem., 66, 3, 281-283, 10.1002/nadc.20184071734
Insight into the complete substrate-binding pocket of ThiT by chemical and genetic mutations
Publikation
Swier L,
Monjas L,
Reeßing F,
Oudshoorn R,
Aisyah,
Primke T,
Bakker M,
van Olst E,
Ritschel T,
Faustino I,
Marrink S,
Hirsch A,
Slotboom D
(2017)
MedChemComm, 8, 5, 1121-1130, 10.1039/c7md00079k, 30108823
MedChemComm, 8, 5, 1121-1130, 10.1039/c7md00079k, 30108823
Saccharide-Containing Dynamic Proteoids
Publikation
Liu Y,
Stuart M,
Witte M,
Buhler E,
Hirsch A
(2017)
Chemistry (Weinheim an der Bergstrasse, Germany), 23, 64, 16162-16166, 10.1002/chem.201703584, 28981987
Chemistry (Weinheim an der Bergstrasse, Germany), 23, 64, 16162-16166, 10.1002/chem.201703584, 28981987
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 4-Aminobutyrate Hydrochloride
Publikation
Nesterkina M,
Shishkina S,
Maltsev G,
Rakipov I,
Kravchenko I
(2017)
Molbank, 2017, 3, 10.3390/M956
Molbank, 2017, 3, 10.3390/M956
Molecular Biodynamers: Dynamic Covalent Analogues of Biopolymers
Publikation
Liu Y,
Lehn J,
Hirsch A
(2017)
Accounts of chemical research, 50, 2, 376-386, 10.1021/acs.accounts.6b00594
Accounts of chemical research, 50, 2, 376-386, 10.1021/acs.accounts.6b00594