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A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
Publikation
Carius P,
Jungmann A,
Bechtel M,
Grißmer A,
Boese A,
Gasparoni G,
Salhab A,
Seipelt R,
Urbschat K,
Richter C,
Meier C,
Bojkova D,
Cinatl J,
Walter J,
Schneider-Daum N,
Lehr C
(2023)
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Adv. Sci., 10, 8, 10.1002/advs.202207301, 36748276
Drug delivery to the inflamed intestinal mucosa- targeting technologies and human cell culture models for better therapies of IBD
Publikation
Olga H,
Shetab Boushehri Maryam A,
Shalaby Karim S,
Brigitta L,
Alf L,
Claus-Michael L
(2021)
Advanced Drug Delivery Reviews, 10.1016/j.addr.2021.113828, 34157320
Advanced Drug Delivery Reviews, 10.1016/j.addr.2021.113828, 34157320
Non-invasive insight into the release mechanisms of a poorly soluble drug from amorphous solid dispersions by confocal Raman microscopy
Publikation
Puncochová K,
Vukosavljevic B,
Hanuš J,
Beránek J,
Windbergs M,
Štepánek F
(2016)
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
European Journal of Pharmaceutics and Biopharmaceutics, 101, 119-25, 10.1016/j.ejpb.2016.02.001, 26861928
Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa - A first in vivo study in human patients
Publikation
Schmidt C,
Lautenschlaeger C,
Collnot E,
Schumann M,
Bojarski C,
Schulzke J,
Lehr C,
Stallmach A
(2013)
Journal of Controlled Release, 165, 2, 139-145, 10.1016/j.jconrel.2012.10.019, 23127508
Journal of Controlled Release, 165, 2, 139-145, 10.1016/j.jconrel.2012.10.019, 23127508
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry
Publikation
Mondal M,
Radeva N,
Fanlo-Virgós H,
Otto S,
Klebe G,
Hirsch A
(2016)
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Angewandte Chemie (International ed. in English), 55, 32, 9422-6, 10.1002/anie.201603074, 27400756
Applications of Raman spectroscopy in skin research--From skin physiology and diagnosis up to risk assessment and dermal drug delivery
Publikation
Franzen L,
Windbergs M
(2015)
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Advanced Drug Delivery Reviews, 89, 91-104, 10.1016/j.addr.2015.04.002, 25868454
Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis
Publikation
Torge A,
Wagner S,
Chaves P,
Oliveira E,
Guterres S,
Pohlmann A,
Titz A,
Schneider M,
Beck R
(2017)
Int J Pharm, 527, 1-2, 92-102, 10.1016/j.ijpharm.2017.05.013, 28499793
Int J Pharm, 527, 1-2, 92-102, 10.1016/j.ijpharm.2017.05.013, 28499793
A new cell line-based coculture model of the human air-blood barrier to evaluate the interaction with aerosolized drug carriers
Publikation
Kletting S
(2016)
Book
Book
Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin
Publikation
Mondal M,
Unver M,
Pal A,
Bakker M,
Berrier S,
Hirsch A
(2016)
Chem. Eur. J., 22, 42, 14826-14830, 10.1002/chem.201603001, 27604032
Chem. Eur. J., 22, 42, 14826-14830, 10.1002/chem.201603001, 27604032
Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening
Publikation
Di Zhu,
Johannsen S,
Masini T,
Simonin C,
Haupenthal J,
Illarionov B,
Andreas A,
Awale M,
Gierse R,
van der Laan T,
van der Vlag R,
Nasti R,
Poizat M,
Buhler E,
Reiling N,
Müller R,
Fischer M,
Reymond J,
Hirsch A
(2022)
Chem. Sci., 13, 36, 10686-10698, 10.1039/D2SC02371G, 36320685
Chem. Sci., 13, 36, 10686-10698, 10.1039/D2SC02371G, 36320685