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Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold
Publikation
Khalifa H,
ElHady A,
Liu T,
Elgaher W,
Filhol-Cochet O,
Cochet C,
Abadi A,
Hamed M,
Abdel-Halim M,
Engel M
(2025)
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243
European journal of medicinal chemistry, 282, 10.1016/j.ejmech.2024.117048, 39566243
Citraconic acid and derivatives thereof for use as a medicament
Publikation
Frank Pessler,
Fangfang Chen,
Moritz Winterhoff,
Konrad Büssow,
Wulf Blankenfeldt,
Anna Hirsch,
Walid A. M. Elgaher
(2024)
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
Patent, A61K31/122; A61K31/194; A61P31/16; C07C57/42; C07C61/20; C07C69/593;, US20240368065A1
New Theophylline Derivatives
Publikation
Elgaher W
(2011)
Book
Book
Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities
Publikation
Hayallah A,
Elgaher W,
Salem O,
Alim A
(2011)
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Arch Pharm Res, 34, 1, 3-21, 10.1007/s12272-011-0101-8, 21468910
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
Publikation
Wagner S,
Sommer R,
Hinsberger S,
Lu C,
Hartmann R,
Empting M,
Titz A
(2016)
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Journal of medicinal chemistry, 59, 13, 5929-69, 10.1021/acs.jmedchem.5b01698, 26804741
Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomes
Publikation
Metelkina O,
Huck B,
O'Connor J,
Koch M,
Manz A,
Lehr C,
Titz A
(2022)
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Journal of Materials Chemistry B, 10, 4, 537-548, 10.1039/d1tb02086b, 34985094
Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery
Publikation
Huck B,
Thiyagarajan D,
Bali A,
Boese A,
Besecke K,
Hozsa C,
Gieseler R,
Furch M,
Carvalho-Wodarz C,
Waldow F,
Schwudke D,
Metelkina O,
Titz A,
Huwer H,
Schwarzkopf K,
Hoppstädter J,
Kiemer A,
Koch M,
Loretz B,
Lehr C
(2022)
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Advanced healthcare materials, 11, 11, 10.1002/adhm.202102117, 35112802
Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
Publikation
Konstantinovic J,
Kany A,
Alhayek A,
Abdelsamie A,
Sikandar A,
Voos K,
Yao Y,
Andreas A,
Shafiei R,
Loretz B,
Schönauer E,
Bals R,
Brandstetter H,
Hartmann R,
Ducho C,
Lehr C,
Beisswenger C,
Müller R,
Rox K,
Haupenthal J,
Hirsch A
(2023)
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
ACS Cent. Sci., 9, 12, 2205-2215, 10.1021/acscentsci.3c01102, 38161367
Fighting antibiotic resistance-strategies and (pre)clinical developments to find new antibacterials
Publikation
Walesch S,
Birkelbach J,
Jézéquel G,
Haeckl F,
Hegemann J,
Hesterkamp T,
Hirsch A,
Hammann P,
Müller R
(2023)
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
EMBO reports, 24, 1, 10.15252/embr.202256033, 36533629
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
Publikation
Frank N,
Széles M,
Akone S,
Rasheed S,
Hüttel S,
Frewert S,
Hamed M,
Herrmann J,
Schuler S,
Hirsch A,
Müller R
(2021)
Molecules, 26, 16, 10.3390/molecules26164929
Molecules, 26, 16, 10.3390/molecules26164929